PSA level determination

Oznaczenie stężenia PSAWhat does PSA level determination involve?

PSA (Prostate Specific Antigen) is a glycoprotein produced by cells of glandular epithelium and is used to diagnose and monitor progression of prostate cancer and benign hyperplasia of this gland.

There are no norms regarding PSA concentration in the blood. It is assumed that as PSA levels increase, the risk of detecting prostate cancer in a given man increases.

According to the guidelines of the European Urological Association - PSA levels> 1ng / ml in age 40 or> 2ng / ml in age 60 should provoke the extension of diagnostics.

However, it should be remembered that PSA is also produced by the healthy prostate epithelium, and it is present in the serum of people with a normal gland, with benign prostatic hyperplasia, as well as those with cancer. The serum level of that antigen also plays an important role. It is estimated that cancer diagnosis is confirmed in nearly ¼ of Patients with PSA levels exceeding 4 ng/ml, and in about 2/3 of Patients with PSA levels exceeding 10 ng/ml.

What is the aim of PSA level determination?

This is a diagnostic test for prostate cancer. Despite its limitations and controversies associated with its use as a "screening" test, the PSA level is the most common test in prostate cancer diagnostics. In coming years, modern tests such as PCA3 and 4Kscore®Test will probably replace this test characterised by limited specificity.

What does the PSA level determination involve?

It is due to its lack of specificity that determination of serum levels of this antigen cannot be the only screening test, and therefore PSA levels determination should be combined with transrectal prostate examination (DRE). The PSA test can be supplemented with determination of free PSA fraction. A free:total PSA ratio can help to interpret a normal or abnormal result of the total PSA level.


Who is this scan for?

The test is intended for Patients over the age of 40.

How can I arrange an appointment for the PSA levels determination?

Please contact us for consultation and confirming the need for the test, using the free online consultation. We will gladly analyse your medical history and answer all your questions.

To arrange the treatment, please contact the Patient coordination department at: + 48 606 994 372 or by email:

See also

PCA3 test

PCA3 is a more precise alternative to the commonly used PSA level determination.


A correct diagnosis of prostate cancer is a very important part of the cancer diagnostic process...

SELECTMDX™ liquid biopsy genetic test

SelectMDx Liquid Biopsy determines the necessity of performing prostate biopsy.

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